Farmiga and Wilson briefly appeared as Ed and Lorraine in the 2024 spin-off film The Nun, focusing on the character of Valak in its "Demon Nun" form, who was the villain from The Conjuring 2.
Sister Irene and Lorraine Warren are revealed to be part of the same bloodline, explaining why both characters are targeted by demons like Valak and Annabelle. The characters played by Taissa and Vera Farmiga are also related in the franchise.